Assessment of assynchronies on pressure time product (PTP) in active pediatric patients

Aim: To reveal the effect of synchronous or asynchronous patients on these values by examining esophageal pressure (Pes ), transpulmonary (PL), and time-pressure-product (PTP) in active who are planned to be weaned from mechanical ventilator can trigger their own respiration.
 Material Methods: Patients monitored a respiration, separated near future, were taken an catheter was inserted, then filling volume first optimized validated, PL started recorded removing Pes airway pressure. With recording devices ventilator, ventilation parameters as both monitoring waveforms. Then, settings rearranged clinician at bedside with reference waveform. waveforms have examined Matlab E2019a (Mathworks, USA) software, each breath marked synchronous-asynchronous asynchrony index (AI) calculated. Accordingly, periods patient defined, ∆Pes, ∆PL, PTP-Pes, PTP-PL, PTP-Pes-minutes, PTP-PL-minutes between same calculated The changes analyzed SPSS statistical program. After distribution variables visual analytical methods (Shapiro-Wilk), difference groups examined.
 Results: When all compared, following differences found favor group. ∆Peso [5.98 (3.55-9.08)] cmH2O, ∆PL [5 (2.7-7.25]cmH2O, ∆PTP-Peso [3.70 (2.81-4.6)) ]cmH2O*s, ∆PTP-PL [3.36 (1.39-4.18)]cmH2O*s, ∆PTP-Peso/min [1.72 (1.02-2.67)]cmH2O*min , ∆PTP-PL/min [1.25 (0.30-3.01)]cmH2O*min.
 Conclusion: It has also been shown analyzes that synchronization respiration causes decrease ∆Peso, ∆Ptranspulmonary, PTP-Peso,PTP-Ptranspulmonary, PTP-Peso-minute, PTP-Ptranspulmonary-minute. this information about is correlated literature, prevent ventilation-related lung damage may occur patients, thus duration hospital stay due asynchrony, failure wean consequences occur. method useful reducing mortality morbidity.